diff --git a/runtime/ftplugin/snakemake.vim b/runtime/ftplugin/snakemake.vim
new file mode 100644
index 0000000000..ab90ca10b5
--- /dev/null
+++ b/runtime/ftplugin/snakemake.vim
@@ -0,0 +1,13 @@
+" Vim filetype plugin
+" Language:	snakemake
+" Maintainer:	Riley Bruins <ribru17@gmail.com>
+" Last Change:	2024 Jun 13
+
+if exists('b:did_ftplugin')
+  finish
+endif
+let b:did_ftplugin = 1
+
+setl comments=:# commentstring=#\ %s
+
+let b:undo_ftplugin = 'setl com< cms<'
diff --git a/runtime/lua/vim/filetype.lua b/runtime/lua/vim/filetype.lua
index cc2fbe0cec..2bb50d8c0b 100644
--- a/runtime/lua/vim/filetype.lua
+++ b/runtime/lua/vim/filetype.lua
@@ -985,6 +985,7 @@ local extension = {
   smt = 'smith',
   smithy = 'smithy',
   sml = 'sml',
+  smk = 'snakemake',
   spt = 'snobol4',
   sno = 'snobol4',
   sln = 'solution',
@@ -1620,6 +1621,7 @@ local filename = {
   ['/etc/slp.spi'] = 'slpspi',
   ['.slrnrc'] = 'slrnrc',
   ['sendmail.cf'] = 'sm',
+  Snakefile = 'snakemake',
   ['.sqlite_history'] = 'sql',
   ['squid.conf'] = 'squid',
   ['ssh_config'] = 'sshconfig',
diff --git a/test/old/testdir/test_filetype.vim b/test/old/testdir/test_filetype.vim
index fa62765398..8bbda1dc99 100644
--- a/test/old/testdir/test_filetype.vim
+++ b/test/old/testdir/test_filetype.vim
@@ -670,6 +670,7 @@ func s:GetFilenameChecks() abort
     \ 'smith': ['file.smt', 'file.smith'],
     \ 'smithy': ['file.smithy'],
     \ 'sml': ['file.sml'],
+    \ 'snakemake': ['file.smk', 'Snakefile'],
     \ 'snobol4': ['file.sno', 'file.spt'],
     \ 'solidity': ['file.sol'],
     \ 'solution': ['file.sln'],