diff --git a/src/nvim/mouse.c b/src/nvim/mouse.c
index 76ac191a68..b8c80cadf5 100644
--- a/src/nvim/mouse.c
+++ b/src/nvim/mouse.c
@@ -220,7 +220,10 @@ static int get_fpos_of_mouse(pos_T *mpos)
   // compute the position in the buffer line from the posn on the screen
   bool below_buffer = mouse_comp_pos(wp, &row, &col, &mpos->lnum);
 
-  if (!below_buffer && *wp->w_p_stc != NUL && mouse_col < win_col_off(wp)) {
+  if (!below_buffer && *wp->w_p_stc != NUL
+      && (wp->w_p_rl
+          ? wincol >= wp->w_width_inner - win_col_off(wp)
+          : wincol < win_col_off(wp))) {
     return MOUSE_STATUSCOL;
   }
 
@@ -675,6 +678,10 @@ popupexit:
       click_col = mouse_col;
     }
 
+    if (in_statuscol && wp->w_p_rl) {
+      click_col = wp->w_width_inner - click_col - 1;
+    }
+
     if (click_defs != NULL) {
       switch (click_defs[click_col].type) {
       case kStlClickDisabled:
@@ -1254,7 +1261,10 @@ retnomove:
   on_sep_line = grid == DEFAULT_GRID_HANDLE && col >= wp->w_width && col - wp->w_width + 1 == 1;
   on_winbar = row == -1 && wp->w_winbar_height != 0;
   on_statuscol = !below_window && !on_status_line && !on_sep_line && !on_winbar
-                 && *wp->w_p_stc != NUL && col < win_col_off(wp);
+                 && *wp->w_p_stc != NUL
+                 && (wp->w_p_rl
+                     ? col >= wp->w_width_inner - win_col_off(wp)
+                     : col < win_col_off(wp));
 
   // The rightmost character of the status line might be a vertical
   // separator character if there is no connecting window to the right.
diff --git a/test/functional/ui/statuscolumn_spec.lua b/test/functional/ui/statuscolumn_spec.lua
index ee235cd6b5..742976cbe2 100644
--- a/test/functional/ui/statuscolumn_spec.lua
+++ b/test/functional/ui/statuscolumn_spec.lua
@@ -532,6 +532,24 @@ describe('statuscolumn', function()
         eq('0 3 r 7', eval("g:testvar"))
         meths.input_mouse('right', 'press', '', 0, 3, 0)
         eq('0 4 r 7', eval("g:testvar"))
+
+        command('rightbelow vsplit')
+        meths.input_mouse('left', 'press', '', 0, 0, 27)
+        eq('0 1 l 4', eval("g:testvar"))
+        meths.input_mouse('right', 'press', '', 0, 3, 27)
+        eq('0 1 r 7', eval("g:testvar"))
+        command('setlocal rightleft')
+        meths.input_mouse('left', 'press', '', 0, 0, 52)
+        eq('0 1 l 4', eval("g:testvar"))
+        meths.input_mouse('right', 'press', '', 0, 3, 52)
+        eq('0 1 r 7', eval("g:testvar"))
+        command('wincmd H')
+        meths.input_mouse('left', 'press', '', 0, 0, 25)
+        eq('0 1 l 4', eval("g:testvar"))
+        meths.input_mouse('right', 'press', '', 0, 3, 25)
+        eq('0 1 r 7', eval("g:testvar"))
+        command('close')
+
         command('set laststatus=2 winbar=%f')
         command('let g:testvar = ""')
         -- Check that winbar click doesn't register as statuscolumn click