diff --git a/.github/workflows/test.yml b/.github/workflows/test.yml
index 5e6f05d973..0d18f874c4 100644
--- a/.github/workflows/test.yml
+++ b/.github/workflows/test.yml
@@ -132,11 +132,11 @@ jobs:
           - flavor: asan
             cc: clang
             runner: ubuntu-22.04
-            flags: -D CLANG_ASAN_UBSAN=ON
+            flags: -D ENABLE_ASAN_UBSAN=ON
           - flavor: tsan
             cc: clang
             runner: ubuntu-22.04
-            flags: -D CLANG_TSAN=ON
+            flags: -D ENABLE_TSAN=ON
           - flavor: uchar
             cc: gcc
             runner: ubuntu-22.04
diff --git a/CMakeLists.txt b/CMakeLists.txt
index 854dc55afa..262af9ab55 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -135,18 +135,18 @@ endif()
 
 option(LOG_LIST_ACTIONS "Add list actions logging" OFF)
 
-option(CLANG_ASAN_UBSAN "Enable Clang address & undefined behavior sanitizer for nvim binary." OFF)
+option(ENABLE_ASAN_UBSAN "Enable Clang address & undefined behavior sanitizer for nvim binary." OFF)
 option(LOG_DEBUG "Enable debug log messages even in a release build" OFF)
-option(CLANG_MSAN "Enable Clang memory sanitizer for nvim binary." OFF)
-option(CLANG_TSAN "Enable Clang thread sanitizer for nvim binary." OFF)
+option(ENABLE_MSAN "Enable Clang memory sanitizer for nvim binary." OFF)
+option(ENABLE_TSAN "Enable Clang thread sanitizer for nvim binary." OFF)
 
-if((CLANG_ASAN_UBSAN AND CLANG_MSAN)
-    OR (CLANG_ASAN_UBSAN AND CLANG_TSAN)
-    OR (CLANG_MSAN AND CLANG_TSAN))
+if((ENABLE_ASAN_UBSAN AND ENABLE_MSAN)
+    OR (ENABLE_ASAN_UBSAN AND ENABLE_TSAN)
+    OR (ENABLE_MSAN AND ENABLE_TSAN))
   message(FATAL_ERROR "Sanitizers cannot be enabled simultaneously")
 endif()
 
-if(CLANG_ASAN_UBSAN OR CLANG_MSAN OR CLANG_TSAN)
+if(ENABLE_ASAN_UBSAN OR ENABLE_MSAN OR ENABLE_TSAN)
   if(NOT CMAKE_C_COMPILER_ID MATCHES "Clang" AND NOT CMAKE_C_COMPILER_ID MATCHES "GNU")
     message(FATAL_ERROR "Sanitizers are only supported for Clang and GCC")
   endif()
diff --git a/CONTRIBUTING.md b/CONTRIBUTING.md
index 91f2ff64dc..c73c205183 100644
--- a/CONTRIBUTING.md
+++ b/CONTRIBUTING.md
@@ -124,7 +124,7 @@ Each pull request must pass the automated builds on [Cirrus CI] and [GitHub Acti
 - If any tests fail, the build will fail. See [test/README.md#running-tests][run-tests] to run tests locally.
 - CI runs [ASan] and other analyzers.
     - To run valgrind locally: `VALGRIND=1 make test`
-    - To run Clang ASan/UBSan locally: `CC=clang make CMAKE_FLAGS="-DCLANG_ASAN_UBSAN=ON"`
+    - To run Clang ASan/UBSan locally: `CC=clang make CMAKE_FLAGS="-DENABLE_ASAN_UBSAN=ON"`
 - The [lint](#lint) build checks modified lines _and their immediate
   neighbors_, to encourage incrementally updating the legacy style to meet our
   [style](#style). (See [#3174][3174] for background.)
@@ -183,7 +183,7 @@ master build. To view the defects, just request access; you will be approved.
 
 - To build Neovim with sanitizers enabled, use
   ```
-  rm -rf build && CMAKE_EXTRA_FLAGS="-DCMAKE_C_COMPILER=clang -DCLANG_ASAN_UBSAN=1" make
+  rm -rf build && CMAKE_EXTRA_FLAGS="-DCMAKE_C_COMPILER=clang -DENABLE_ASAN_UBSAN=1" make
   ```
 - When running Neovim, use
   ```
@@ -294,7 +294,7 @@ If a function in your Lua module should not be documented (e.g. internal functio
 ---@private
 ```
 
-Mark functions that are deprecated as 
+Mark functions that are deprecated as
 ```
 ---@deprecated
 ```
diff --git a/cmake.deps/cmake/BuildLua.cmake b/cmake.deps/cmake/BuildLua.cmake
index 2817418eb2..3e7b5dee51 100644
--- a/cmake.deps/cmake/BuildLua.cmake
+++ b/cmake.deps/cmake/BuildLua.cmake
@@ -19,7 +19,7 @@ endif()
 set(LUA_CFLAGS "-O0 -g3 -fPIC")
 set(LUA_LDFLAGS "")
 
-if(CLANG_ASAN_UBSAN)
+if(ENABLE_ASAN_UBSAN)
   set(LUA_CFLAGS "${LUA_CFLAGS} -fsanitize=address")
   set(LUA_CFLAGS "${LUA_CFLAGS} -fno-omit-frame-pointer")
   set(LUA_CFLAGS "${LUA_CFLAGS} -fno-optimize-sibling-calls")
diff --git a/contrib/asan.sh b/contrib/asan.sh
index 7e7dffa1af..baf7abb5a8 100755
--- a/contrib/asan.sh
+++ b/contrib/asan.sh
@@ -16,7 +16,7 @@ export ASAN_OPTIONS="detect_leaks=0:log_path=$log_path/asan"
 # Show backtraces in the logs.
 export UBSAN_OPTIONS="print_stacktrace=1"
 
-make -C "$root_path" CMAKE_EXTRA_FLAGS="-DCLANG_ASAN_UBSAN=ON"
+make -C "$root_path" CMAKE_EXTRA_FLAGS="-DENABLE_ASAN_UBSAN=ON"
 VIMRUNTIME="$root_path"/runtime "$root_path"/build/bin/nvim
 
 # Need to manually reset terminal to avoid mangled output, nvim does not
diff --git a/contrib/flake.nix b/contrib/flake.nix
index 3884ee9a2b..75c94392e1 100644
--- a/contrib/flake.nix
+++ b/contrib/flake.nix
@@ -48,7 +48,7 @@
           ] ++ final.lib.optionals final.stdenv.isLinux [
             # https://github.com/google/sanitizers/wiki/AddressSanitizerFlags
             # https://clang.llvm.org/docs/AddressSanitizer.html#symbolizing-the-reports
-            "-DCLANG_ASAN_UBSAN=ON"
+            "-DENABLE_ASAN_UBSAN=ON"
           ];
         });
       };
diff --git a/src/nvim/CMakeLists.txt b/src/nvim/CMakeLists.txt
index b348520616..2117bc375c 100755
--- a/src/nvim/CMakeLists.txt
+++ b/src/nvim/CMakeLists.txt
@@ -200,9 +200,9 @@ endif()
 
 option(ENABLE_GCOV "Enable gcov support" OFF)
 if(ENABLE_GCOV)
-  if(CLANG_TSAN)
+  if(ENABLE_TSAN)
     # GCOV and TSAN results in false data race reports
-    message(FATAL_ERROR "ENABLE_GCOV cannot be used with CLANG_TSAN")
+    message(FATAL_ERROR "ENABLE_GCOV cannot be used with ENABLE_TSAN")
   endif()
   message(STATUS "Enabling gcov support")
   target_compile_options(main_lib INTERFACE --coverage)
@@ -378,7 +378,7 @@ else()
   target_compile_definitions(nvim PRIVATE $<$<CONFIG:Debug>:NVIM_LOG_DEBUG>)
 endif()
 
-if(CLANG_ASAN_UBSAN OR CLANG_MSAN OR CLANG_TSAN)
+if(ENABLE_ASAN_UBSAN OR ENABLE_MSAN OR ENABLE_TSAN)
   target_compile_definitions(main_lib INTERFACE EXITFREE)
 endif()
 
@@ -791,7 +791,7 @@ set_target_properties(
 target_compile_definitions(libnvim PRIVATE MAKE_LIB)
 target_link_libraries(libnvim PRIVATE main_lib PUBLIC libuv)
 
-if(CLANG_ASAN_UBSAN)
+if(ENABLE_ASAN_UBSAN)
   message(STATUS "Enabling Clang address sanitizer and undefined behavior sanitizer for nvim.")
   if(CI_BUILD)
     # Try to recover from all sanitize issues so we get reports about all failures
@@ -805,7 +805,7 @@ if(CLANG_ASAN_UBSAN)
     -fsanitize=address
     -fsanitize=undefined)
   target_link_libraries(nvim PRIVATE -fsanitize=address -fsanitize=undefined)
-elseif(CLANG_MSAN)
+elseif(ENABLE_MSAN)
   message(STATUS "Enabling Clang memory sanitizer for nvim.")
   target_compile_options(nvim PRIVATE
     -fsanitize=memory
@@ -813,7 +813,7 @@ elseif(CLANG_MSAN)
     -fno-omit-frame-pointer
     -fno-optimize-sibling-calls)
   target_link_libraries(nvim PRIVATE -fsanitize=memory -fsanitize-memory-track-origins)
-elseif(CLANG_TSAN)
+elseif(ENABLE_TSAN)
   message(STATUS "Enabling Clang thread sanitizer for nvim.")
   target_compile_options(nvim PRIVATE -fsanitize=thread -fPIE)
   target_link_libraries(nvim PRIVATE -fsanitize=thread)
diff --git a/src/nvim/README.md b/src/nvim/README.md
index 5a6d63c662..69d5939c70 100644
--- a/src/nvim/README.md
+++ b/src/nvim/README.md
@@ -60,9 +60,9 @@ Requires clang 3.4 or later, and `llvm-symbolizer` must be in `$PATH`:
 
 Build Nvim with sanitizer instrumentation (choose one):
 
-    CC=clang make CMAKE_EXTRA_FLAGS="-DCLANG_ASAN_UBSAN=ON"
-    CC=clang make CMAKE_EXTRA_FLAGS="-DCLANG_MSAN=ON"
-    CC=clang make CMAKE_EXTRA_FLAGS="-DCLANG_TSAN=ON"
+    CC=clang make CMAKE_EXTRA_FLAGS="-DENABLE_ASAN_UBSAN=ON"
+    CC=clang make CMAKE_EXTRA_FLAGS="-DENABLE_MSAN=ON"
+    CC=clang make CMAKE_EXTRA_FLAGS="-DENABLE_TSAN=ON"
 
 Create a directory to store logs: